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By acting as a cofactor for 11-hydroxylase, for instance, the ascorbate somewhat increases the conversion of 11-deoxycortisol to cortisol and keeps the cortisol tone at physiological levels (104)

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William Silverstein of the University of Toronto

eNOS, located in the vascular endothelium, regulates vascular tone, while iNOS is induced in immune cells and helps in host defense mechanisms

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