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This means both copies of a gene in each cell have mutations
If you have other conditions that make surgery dangerous, your doctor may recommend radiation therapy, cryosurgery, or topical imiquimod (Aldara, Zyclara)

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doi: 10.1111/all.13352
Pattern Recogn 30(7):11451159 Celebi ME, Zornberg A (2014) Automated quantification of clinically significant colors in Dermoscopy images and its application to skin lesion classification

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