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Early Life Growth Hormone Treatment Shortens Longevity and Decreases Cellular Stress Resistance in Long-Lived Mutant Mice

[DOI] [PMC free article] [PubMed] [Google Scholar] 250.Chang C.L., Weigel A.V., Ioannou M.S., Pasolli H.A., Xu C.S., Peale D.R., Shtengel G., Freeman M., Hess H.F., Blackstone C., et al

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This shortage inhibits tissue uptake, resulting in reduced accumulation in the skeletal muscle and heart, as well as potentiating increased renal carnitine loss (Burwinkel et al., 1999, Y et al.., 1999), resulting in systemic carnitine depletion (Reuter et al., 2008)

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