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It has been reported that an up-regulation of TRPV1, TRPA1 and the Na V 1.6 sodium channel after chemotherapeutic exposure is responsible for the heat/cold evoked pain response [26-29]

doi: 10.1093/toxsci/67.2.322

They differ fundamentally in what is implanted: DBS implants a device (an electrode)

doi: 10.1016/j.redox.2016.12.035 7 SiesHBerndtCJonesDP

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Mt nh gi rt ra t 29 nghin cu trn nhng ngi khe mnh cho thy b sung vitamin C lm gim mc huyt p tm thu 3.8 mmHg v huyt p tm trng 1.5 mmHg