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For example, some studies suggest that long-term glutathione use can be linked to lower zinc levels

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Furthermore, because mixed micelles composed of bile acids, phosphatidylcholine, and cholesterol are osmotically active and the tight junctions that link adjacent hepatocytes are relatively leaky, water is drawn into the canalicular lumen, as well as other plasma solutes, such as Ca ++ , glucose, glutathione, amino acids, and urea, at concentrations essentially approximating those in plasma ( Fig