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Overexpression of the phgdh gene has been observed in colon 126 and gastric cancers 127 , and is associated with poor prognosis, higher tumor grade and larger tumor sizes in CRC 128

Valko et al., 2007)
[DOI] [PubMed] [Google Scholar] 18.Zhang HT, Zhang P, Gao Y, Li CL, Wang HJ, Chen LC, et al

Delivery of oligonucleotide-based therapeutics: challenges and opportunities

Dan and Baldwin [81] revealed that insulin and TNF activated mTOR through both the AKT/mTOR and the AKT/IKK/mTOR pathways, whereas TNF also activated mTOR via the IKK-mediated signaling independently of the PI3K/AKT pathway in several cell types

Mater Sci Engineering: C
