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doi:10.1016/j.ymthe.2018.06.001 Quixabeira DCA, Zafar S, Santos JM, et al

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doi: 10.1056/NEJMoa0907929

Among other things, this is due to the fact that patients with pyruvate dehydrogenase deficiency are in a way dependent on food-derived glucose, as gluconeogenesis itself is impaired in these individuals [59]