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These results show that leukocyte-derived sources of IL-6 are critical in mediating the behavioral effects of repeated social stress, although it is not yet clear how peripheral IL-6 modulates susceptibility

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They are vital for various bodily functions and must be obtained through diet or supplementation

746 HSP90 appears to play additional roles in maintaining an immunosuppressive phenotype, as a low level of HSP90 inhibition, which is not sufficient to inhibit the HSR or UPR, or affect PD-L1 expression or localization, increases MHC-I presentation at the cell surface

doi: 10.3389/fendo.2019.00206

The foundational biochemistry paper proposing direct HGF binding was retracted, so even the mechanism is a working hypothesis rather than a settled fact