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O 2 is the precursor of most ROS

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Mitochondrial ROS-induced ROS release: an update and review

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Additionally, endogenous antioxidants such as glutathione (GSH), melatonin, and N-acetylcysteine (NAC) play essential roles in maintaining redox balance, detoxifying ROS, and protecting mitochondrial integrity

Non-Neoplastic Proliferative Lesions Introduction A variety of non-neoplastic proliferative lesions of different origin(s) occurs spontaneously in the liver of rodents and may also be induced by treatment with chemicals
