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Clinical trial studies demonstrated that low systemic bioavailability of curcumin is observed in human following oral administration

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Therefore, ferroptosis may provide an alternative strategy for killing PDAC cells and overcoming apoptosis resistance (Chen X

While ammonium accumulation-mediated acidification has been experimentally validated ( in vitro and in vivo ) to drive immunosuppression in the prostate cancer TME, primarily through impairing T cell and NK cell cytotoxicity and promoting M2 macrophage polarization

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