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Indeed, excessive ROS disrupt the BBB integrity, impairing its selective permeability (Hu et al., 2020)

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While acknowledging that this was a relatively small retrospective study ( n = 81), the results suggest that in the future, pending further evidence, acetyl-l-carnitine might be considered as an addition to first-line treatments currently recommended by IASP

10.21203/rs.3.rs-23528/v1 96

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