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In this case, it is hypothesized that Lyme disease triggered the polyarthritis in susceptible individuals, such as those with a history of psoriasis, but that it is not due to active infection of the joint

doi:10.1631/jzus.B1100329
In animal studies, yes

Unlike many conventional drugs that act broadly throughout the body, peptides can be engineered to target specific tissues or processes, maximizing their therapeutic potential

Painter and Burkitt first elucidated this connection after noting the striking disparity in incidence between British society and sub-Saharan populations
