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Disrupting this signaling circuit with the selective inhibitor SP600125 restores mitochondrial membrane potential, curtails keratinocyte hyper proliferation and cytokine release in vitro, and markedly mitigates epidermal hyperkeratosis and inflammation in an imiquimod induced psoriasis model, highlighting JNK inhibition as a promising strategy for redox driven skin pathology

Free Rad Res 54(1):126 Chen W-J, Lin K-H, Lee Y-S (2000) Molecular characterization of myocardial fibrosis during hypothyroidism: evidence for negative regulation of the pro-1 (I) collagen gene expression by thyroid hormone receptor

10.4049/jimmunol.1501756 182 MikoE.MargitaiZ.CzimmererZ.VarkonyiI.DezsoB.LanyiA.et al

Selenium in soil and endemic diseases in China

A novel selenium analog of HDACi-based twin drug induces apoptosis and cell cycle arrest via CDC25A to improve prostate cancer therapy

In GWAS of differentiated thyroid cancer, associations at FOXE1, MAP3K12 binding inhibitory protein 1 (MBIP)-NK2 homeobox 1 (NKX2-1), disrupted in renal carcinoma 3 (DIRC3), neuregulin 1 (NRG1), and pecanex-like 2 (PCNXL2) have been commonly identified in people of European and Korean ancestry, and many other susceptibility loci have been found in specific populations