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The search focused on human studies published over the last four decades, prioritising randomised controlled trials (RCTs) and meta-analyses to ensure strong clinical evidence

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Egger M, et al

For instance, variations in the prevalence of genetic polymorphisms such as PNPLA3 and TM6SF2, both strongly associated with NAFLD susceptibility and progression in Chinese populations, may impact the effectiveness of GSH treatment [113,114,115,116]

In most cases, LOX may not be the primary driver of ferroptosis, but it may contribute to the initiation or spread of damage

Front Oncol 11:679816 Li H, Cao Z, Wang L, Liu C, Lin H, Tang Y, Yao P (2022a) Macrophage subsets and death are responsible for atherosclerotic plaque formation