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The metabolism of chloroquine and hydroxychloroquine differs only in the number of metabolites produced (Fig

The COA included endotoxin and sterility data which our lab requires. Both batches came well within TFA acceptable limits
ROS and chromatin ROS influence the activity of epigenetic modulators, such as histone deacetylases (HDACs) or DNA methyltransferases (DNMTs) with consequences that are evident in the expression of the target genes 38,39
