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Limitations of the current study

Mice treated with MOTS-c showed dramatic resistance to diet-induced obesity even without changes in caloric intake

Cell Res (2023) 33:1129

The results of this analysis were consistent with our in vitro experiments, showing that GCLC overexpression alleviated MPTP-induced oxidative stress and inflammation

thus, the serum concentrations of all analytes were assessed between time 1 and 2 (T1 and T2) to monitor disease progression

The investigators explored MOR hyperpolarization of other thalamic neurons (principal relay, midline, and intralaminar nuclei) and found widespread MOR-mediated inhibition of thalamic neurons, suggesting that the thalamus is a highly sensitive region to MOR-mediated neuronal hyperpolarization (Brunton and Charpak, 1998)