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Whereas the tolerability profile of NAC appears benign, it needs to be stressed that there is no extensive evidence base with longer-term use

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After interruption of gemcitabine and symptomatic treatment, the evolution of haemolytic anaemia was generally favourable, but this was not the case for renal dysfunction: two complete and one partial resolution of renal insufficiency were noted, but one case required chronic dialysis

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10.1016/j.femsle.2005.08.049 [DOI] [PubMed] [Google Scholar] Zhao C., Gao L., Wang C., Liu B., Jin Y., Xing Z

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J Transl Med 10(1):11

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Superoxide radical (O 2 ) was visualized with dihydroethidium (DHE) by placing the seedlings in DHE solution (10 M DHE in 10 mM, TrisHCl buffer, pH 7.4) for 30 min at 37 C

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