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In contrast, intracerebroventricular administration of deferoxamine (DFO) improves striatal pathology and motor phenotype in R6/2HD mice ( Cell stress response to ROS includes the activation of pro-survival pathways as well as the production of molecules endowed with antioxidant and anti-apoptotic activities, which is under the control of protective genes called vitagenes (Wu, 1995)

Jantaruk P, Roytrakul S, Sitthisak S, Kunthalert D

Similarly, inhibition of mTOR reduces the levels of glycine, asparagine, glutamine, and proline, all of which are essential for fibroblast activation and matrix deposition [111]

Another showed NAC improved lung function by 4.6% (NIH)

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