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Gene expression signatures of cAMP/protein kinase A (PKA)-promoted, mitochondrial-dependent apoptosis

You may also consider using a viral-based system ( to deliver your gene into your mammalian cell line of interest

J Thromb Haemost 2010

Key facts from Pickarts original studies: GHK-Cu exists in the plasma of all healthy adults The concentration decreases with age , from ~200 ng/ml in 20-year-olds to ~80 ng/ml in 60-year-olds This decline correlates with the age-related loss of regenerative capacity of tissue Cu is essential for the biological activity, GHK without copper has a dramatically weaker effect These original observations launched a 50-year research program that today covers thousands of publications in dermatology, wound healing, ageing research and regenerative medicine

doi:10.1016/S0969-2126(02)00933-4 ^ Kabashima T., Kawaguchi T., Wadzinski B.E., Uyeda K

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