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Main body Two of the main players in the molecular and cellular response to OS are NRF2, the transcription nuclear factor erythroid 2-related factor 2, and its principal negative regulator, KEAP1, Kelch-like ECH (erythroid cell-derived protein with CNC homology)-associated protein 1

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Results: A 14-y-old patient with a body mass index of 12.6kg/m2 presented with markedly elevated transaminases (ALAT >50 upper limit of normal), and paracetamol was detected in her blood