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Cancer Cell 17 , 121134 (2010)

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This enhances the cytotoxic response of T cells, thereby improving immunotherapy efficacy

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Unlike traditional inorganic materials that rely predominantly on ROS generation, Cu-Mn NPs depend on Mn ions released in local tissues to enhance the antimicrobial immune response through stimulation of interferon (IFN) and pro-inflammatory cytokines via the cGAS-STING signaling pathway