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Total body water was determined with bioelectrical impedance spectroscopy (TBF-410GS, Tanita Inc., Arlington Heights, IL, USA) using a low energy, high frequency current (500 micro amps at a frequency of 50 kHz)

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Clarifying the link between the mechanisms and features of the effects of these substances (especially multi-target compounds), while investigating the potential for combination therapies and formulating more targeted stimulators or repressors, will significantly influence their clinical application

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It works by increasing the activities of antioxidant enzymes like SOD and GSH while decreasing lipid peroxidation markers such as MDA (Menon & Sudheer, 2007)