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Nat Med, 2003

Silvestro S, Raffaele I, Quartarone A, Mazzon E

Update of the hyper-CVAD and Imatinib mesylate regimen in Philadelphia (Ph) positive acute lymphocytic leukemia (ALL)

doi:10.1177/15648265080292S107

Supported by the substantial weight-loss efficacy of the GLP-1MK-801 conjugate and the potentiated hypothalamic changes in transcripts and proteins related to NMDA receptor-linked neuroplasticity, the alteration in MK-801 biodistribution governed by GLP-1-mediated targeting may effectively bypass the delivery of MK-801 to vagal afferent target neurons in the nucleus of the solitary tract

This causal evidence was, however, not supported by a population study using SLC2A9 and ABCG2 SNPs