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5-Aminosalicylic acid (5-ASA, batch number A129982) was purchased from Aladdin
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The inhibition of the CySS/Glu antiporter system reduces GSH synthesis and GPX4 inactivation, leading to the accumulation of polyunsaturated fatty acids (PUFA) and ROS, and causing membrane integrity damage and ferroptosis (Friedmann Angeli and Conrad, 2018
Challenges in the field of senotherapy for AD, including target engagement and biomarker development, are addressed
Although glutathione is included in the treatment plan of many diseases, it has no proven effect on diseases
