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In those situations, alternative treatment options may be more appropriate and can be discussed with a clinician

IF induces sirtuin-1 (SIRT1) expression, which enhances mitochondrial biogenesis and promotes deacetylation of autophagy-related proteins, thus facilitating the removal of damaged mitochondria and misfolded proteins [67]

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Protamine sulfate induced bladder injury protects from distention induced bladder pain