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Heffernan MA et al

[Abstract]2026 Feb 21

Regulatory Status and Quality Control One important point often overlooked in marketing: AOD9604 is not FDAapproved for fat loss or aesthetic use

Morning administration in a fasted state is the most commonly cited timing because endogenous fat mobilisation is naturally elevated after an overnight fast, theoretically amplifying the lipolytic signal from the peptide

The difference between optimal and suboptimal timing is the difference between sustained NNMT suppression and sporadic enzyme inhibition that your metabolism compensates for within hours

Confirming the deficiency with a blood test is what makes that trade-off clear