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Cuzzocrea S, Tan DX, Costantino G, Mazzon E, Caputi AP, Reiter RJ

Cell 187 , 18341852.e19 (2024)

Neuroprotective effects of GYKI 52466 on experimental spinal cord injury in rats

Additionally, there are drug efflux pumps such as p -glycoprotein (P-gp), multidrug resistance associated protein (MRP) and drug metabolic enzymes, at the BBB to remove and/or inactivate small drug molecules from the brain [1]

[DOI] [Google Scholar] 75.Shevchenko N., Iakobson O., Isakov V., Zorin I

While this works for many, not everyone absorbs vitamin C efficiently, and some individuals may need higher doses than oral supplements can provide