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Therefore, defects in the ability of red blood cells to reduce NADP+ to NADPH compromise this protection system and lead to oxidative damage, ultimately causing rupture of the red blood cell membrane and hemolysis

Research has suggested that glutathione may have several health benefits, including reducing the risk of chronic diseases such as Alzheimers, Parkinsons, and heart disease

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Molinar VE, Taylor SC, Pandya AG

Crit Care Med (2005) 33(3):56473.10.1097/01.CCM.0000155991.88802.4D 63 XiangZSnouwaertJNKovarovaMNguyenMRepenningPWLatourAMet alMice lacking three Loci encoding 14 glutathione transferase genes: a novel tool for assigning function to the GSTP, GSTM, and GSTT families

LCS3 is a synergistic inhibitor of GSR and TXNRD1