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Bi-allelic alterations in AEBP1 lead to defective collagen assembly and connective tissue structure resulting in a variant of EhlersDanlos syndrome

After first use (first needle puncture), the vial should be used within 28 days

This is comparable to tirzepatide fridge life and semaglutide fridge life

a reconstituted B12 preparation may be stable for considerably longer

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Inverse variance weighting (as main analysis), weighted median estimate, robust adjusted profile score, MR-Egger, and MR-PRESSO (sensitivity analyses) were performed to calculate causal estimates