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Use in pregnancy is not recommended unless the potential benefit justifies the potential risk to the fetus

All of these patients who were treated orally corrected their vitamin B12 levels and at least 80% corrected their hematological abnormalities [26]
H.KrausJ

PMCID: PMC7489598
Hsieh et al., 2020) but are rarely paired with the in vivo healing studies

NAD + repletion improves mitochondrial and stem cell function and enhances life span in mice