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Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice

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Room temperature storage for lyophilized peptides should be considered only for very short-term use, maybe a few days, before reconstitution

GCLC, glutamate-cysteine ligase catalytic subunit

This minimizes waste while providing enough doses to complete the starting phase

It has also been shown that exposure of brain microvessels to hyperglycemic condition or AGEs ex vivo results in the abnormalities in tight junction protein distributions