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The mechanism of action is associated with direct stimulation of the dopamine D2 receptors of the lactotropic pituitary cells

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The release of Nrf2 from Keap1 is also achieved by its phosphorylation on Ser40 by several kinases such as protein kinase C (PKC), casein kinase-2 (CK2), phosphoinositide-3-kinase (PI3K), c-Jun NH 2 -terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and protein kinase RNA-like ER kinase (PERK) (82)

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