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A neuroendocrine carcinoma was considered less likely
Unlike hepatocytes, which are potentially transfected by current LNPs via endogenous apolipoprotein mediated uptake, successful mRNA delivery to other tissues involves multiple additional hurdles after nanoparticles (NPs) accumulation, including cellular internalization, endosomal escape, and cytoplasmic release required for functional mRNA expression
Our experience indicates that injections produce essentially the most favorable outcomes amongst sufferers
Tumor imaging and therapy using radiolabeled somatostatin analogues
Acute SCI Management: Nonoperative Considerations Thomas Land Publication
Biochemistry 43 , 68996908, (2004)
