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The binding of aspirin to the RNA and acetylation of an activated 2-OH could in theory change the splicing pattern of a gene, therefore producing an alternative RNA isoform and protein product

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February 28, 2022

The thiol-disulfide equilibrium within the cell is known to regulate a diverse number of metabolic processes including enzyme activity, transport activity, signal transduction, and gene expression via alteration of redox sensitive transcription factors such as activator protein-1 (AP-1), nuclear factor kappa B (NFB) and p53 (Hutter et al., 1997