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doi: 10.1007/s004010000284, 104 MllerJ.BhatK.GuhlL.PrtnerR.JandtU.ZengA

Melatonin counteracts oxidative damage in lens by regulation of nrf2 and nlrp3 inflammasome activity

Acknowledgements We thank J.E
Epub 2020 Aug 27

Moreover, the study also identified that NADPH oxidase subunit gp 91 phoxin was upregulated in the MPG after CNI, indicating that NADPH oxidase may be another source of oxidative stress in the MPG

The majority of renoprotective claims derive from rodent models (primarily db/db mice, streptozotocin-induced diabetes, or high-fat diet models), which exhibit fundamental differences from human DKD in gut microbiota composition, metabolic kinetics, and disease progression timelines
