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The mechanisms already discussed, including enhanced angiogenesis, increased fibroblast activity, collagen synthesis upregulation, and improved cell migration, all contribute to faster resolution of tissue damage

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Mutations at the helix 23 and helix 14 FAT-paxillin binding sites inhibit FAK localization, FAK and paxillin phosphorylation, focal adhesion turnover, cell adhesion, migration, and invasion 25,26,28

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Whilst caloric restriction is therapeutically appropriate, inadequate attention to dietary quality and micronutrient density can result in nutritional deficiencies , including B12, folate, iron, and other essential nutrients

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