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In this sense, adjunctive therapies for specific tumors using these modulators can further improve immunotherapies

317 Researchers have found that Fer-1 binds to 15LOX/phosphatidylethanolamine binding protein-1 (PEBP1) complex, suppressing the generation of peroxidized eicosatetraenoyl-phosphatidylethanolamine (ETE-PE) and protecting against ferroptosis

Through both of these mechanisms, ROS play an important role in cancer development (i.e., carcinogenesis), atherosclerosis, diabetes, inflammation, aging, and other harmful processes

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