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A significant breakthrough in understanding this phenomenon comes from a study by Zhang et al in Nature , which identified norepinephrine (noradrenaline) as a key factor in stress-induced hair graying

[DOI] [PMC free article] [PubMed] [Google Scholar] 226.Shintani T, Sakoguchi H, Yoshihara A, et al

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In addition, iFSP1 was shown to inhibit FSP1 in a species-dependent manner, revealing structural features that confer selectivity for the human enzyme 120
Natural Products-Based Nanoformulations: a New Approach Targeting CSCs to Cancer Therapy