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NNMT alters Akt phosphorylation and affects the association between the transcription factor SP1 and the MMP2 promoter (50)
Fat-loss and metabolic compound comparison Compound 5-Amino-1MQ Mechanism NNMT inhibitor

In lipodystrophy, patients lack adipose tissue due to genetic mutations in the ability to properly form functional adipocytes or to store FAs as TAGs (168)
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