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These follicle-like cells (FLCs) express oocyte-specific markers, providing a platform for investigating human germ cell development and gene mechanisms, including noncoding RNAs (Jung et al., 2017

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It was eventually discovered that the cis orientation of the leaving groups allowed binding of two adjacent guanine bases on the same strand, which resulted in a large kink in the DNA helix, causing polymerases to be stalled at the kink