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It was found that the thiazole ring had been opened, creating a disulfide
This is a similar mechanism to methylene blue, another targeted rescue therapy for vasoplegic shock, which acts as a competitive antagonist of NO to inhibit its vasodilatory effects [14]
7 -blockers like propranolol can suppress flushing reactions, but the side effects of hypotension and bradycardia can pose problems
Zhao N, Xia J, Xu B
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