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Notably, overcoming age-related impairments in MCUR1-dependent mtCa uptake enhances mitochondrial metabolism and muscle function, significantly restoring mitochondrial activity and physical performance in aged mice [294]

Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells

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While therapeutic strategies such as iron chelation and ferroptosis inhibition appear promising in alleviating iron overloadassociated tissue injury in experimental settings, there is insufficient clinical evidence to support their use in OSAS patients at present