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Various factors may have contributed to these mixed results, including participant heterogeneity, compliance issues, and the aggressive placebo response often seen in obesity trials where lifestyle modification is encouraged

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10.1042/bj3230159 188 LiuJ.Garcia-CardenaG.SessaW

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Exp Neurobiol 169:219230 Mount MP, Lira A, Grimes D, Smith PD, Faucher S, Slack R, Anisman H, Hayley S, Park DS (2007) Involvement of interferon- in microglial-mediated loss of dopaminergic neurons