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& Siegal, A

These carriers are typically made of high-density polyethylene (HDPE)

As a result, Frye says, he and other researchers typically use a less reliable measure: the presence of folate-blocking antibodies in a child's blood

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All these factors may affect the sensitivity and specificity of serum B12 as a biomarker of B12 status and result in false-positive or false-negative classification of vitamin B12 deficiency
