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Description
It improves blood flow, enhances oxygen and nutrient delivery to muscles, supports cardiovascular health, and may even boost exercise performance and recovery
2020 Nov 4;2020:7397480
1 (8.33%) patient with severe vasculogenic ED and 1 (2.86%) patient with mildmoderate vasculogenic ED dropped out at T1
Both 4hydroxyhexenal and 4hydroxynonenal at low concentrations are protective against oxidative stress by triggering the Nrf2 pathway, which regulates the expression of antioxidant proteins including heme oxygenase-1, a potent antioxidant enzyme, and they can induce other cytoprotective pathways and enhance expression of other detoxification genes
The ultimate therapeutic dose should be achieved on the basis of both tolerability and clinical response [see Warnings and Precautions(5.16), Use in Specific Populations (8.5), and Clinical Pharmacology(12.3)]
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