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This is the reply I had from my doctor

Injection site rotation prevents localized irritation

Who needs B12 injections and how often they are needed depends on the individual patient and is determined on a case-by-case basis

Its effects on dopamine and norepinephrine could fall under non-specified stimulants if flagged during screening

These types are called vitamin B12 non-responsive. One of these is called Mut 0. It is caused by the absence of an enzyme called methylmalonyl-CoA mutase (MCM)
The amount of time required for Me 12 500 MCG Injection to show its action is not clinically established
