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The resulting inflammation exacerbates tissue damage and contributes to adverse remodeling of the heart, which can lead to heart failure if not properly managed [93]
94, 109115.10.1016/S0079-6123(08)61743-4 103 NicklasW
Notably, chronic stress can trigger epigenetic modifications, reprogramming astrocytes into disease-associated reactive states with distinct molecular profiles compared with normal astrocytes 9,11
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Human microvascular endothelial cells immortalized with human telomerase catalytic protein: a model for the study of in vitro angiogenesis
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