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12,26 Furthermore, the formation of NAPQI adducts contributes to oxidative stress, mitochondrial dysfunction, disrupted Ca 2+ homeostasis, necrotic cell death, centrilobular necrosis, and eventual liver failure (Figs
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
Thus, APAP hepatotoxicity contributes to around 70,000 hospitalizations each year in the US5
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