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However, these APIs are frequently abused beyond medical and therapeutic context, including athletes and recreational users, causing serious public health concern (Napper et al., 2010)

10.1038/cr.2014.106 149 LomonacoM.MiloneM.BatocchiA

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Increased NO activity can promote wakefulness and alertness in the short term (PubMed)

Toll-Like Receptor 2 Enhances ZO-1-associated Intestinal Epithelial Barrier Integrity Via Protein Kinase C

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