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Moderate deficit works best: 300-500 calorie deficit below maintenance
If you need laxatives every day, then you should see your doctor to find the cause of your constipation

The cause is debated in the research literature, but the experience is real: fatigue, joint pain, cognitive difficulty, and sleep disruption that persist long after the antibiotic course ends

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In pathophysiological conditions, PKD-mediated phosphorylation of Ser637 has been demonstrated to enhance mitochondrial fragmentation (Jhun et al., 2018)
